Every five years, the ISRP provides a great opportunity to present the state-of-the-art thinking and practice in ruminant physiology to an international audience of scientists. In a tradition going back more than 60 years, the symposium is an excellent venue at which to assemble researchers in the field of ruminant physiology. There is no other international scientific symposium that offers such depth of this topic. American Dairy Science Association was honored to bring this event to the United States and America's Heartland in 2024.